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What Is SIBO: SIBO stands for small intestinal bacterial overgrowth and occurs when bacteria, both friendly and unfriendly strains, overgrow in the small intestine. Overgrowth of bacteria in the small intestine can lead to many adverse gastrointestinal symptoms. Symptoms of SIBO: Abdominal bloating, especially after eating Burping Gas Indigestion Reflux / GERD Nausea Abdominal pain Constipation and/or diarrhea Undigested food in stool Food intolerances / sensitivities Environmental allergies Anemia - iron deficiency anemia, vitamin B12 deficiency anemia, or anemia of unknown origin Fatigue Brain fog Poor concentration Anxiety Depression Joint pain, usually in combination with gastrointestinal symptoms Muscle pain, usually in combination with gastrointestinal symptoms ADD / ADHD Skin conditions - rashes, eczema, psoriasis, rosacea Itching Changes in weight - weight loss or weight gain May be asymptomatic Causes of SIBO: It is commonly believed that SIBO occurs when bacterial species in the colon overgrow in the small intestine; however, this is not always the case. Other factors that may contribute to the formation of SIBO, some of which include the following: Oral antibiotics Other acute or chronic microbial imbalances in the gastrointestinal tract (bacteria, viruses, parasites) Food poisoning Low gastrointestinal immune function Poor drainage of the intestines Delayed gastrointestinal motility Constipation Gastric bypass surgery Drinking chlorinated water Long-term use of antacids or proton pump inhibitors Certain medications Smoking Pesticides Types of SIBO: Small intestinal overgrowth is differentiated into methane, hydrogen, and/or hydrogen sulfide positive SIBO based on the types of gases produced during SIBO diagnostic tests. Conventional SIBO Diagnosis: The gold standard for diagnosing SIBO is a jejunal aspirate, which is highly invasive, expensive, and has limited ability to assess the entire small intestine. Breath tests are the most common conventional method used to diagnose SIBO. Patients must follow a specific bland diet for multiple days leading up to the breath test and fast the day of the test. The morning of the breath test, a single dose of liquid lactose, fructose, or glucose is ingested. A series of breath samples are taken throughout the day and then sent to a lab for gas analysis. Positive SIBO breath tests occur when bacteria ferment the ingested sugar solution and produce methane, hydrogen, and/or hydrogen sulfide gas. The accuracy of SIBO breath tests is highly limited and prone to user error. False-positive tests may result in certain cases of large intestine bacterial overgrowth, rather than bacterial overgrowth occurring in the small intestine. In many cases, SIBO extends beyond the parameters of conventional testing. It is possible for species other than those that give off methane, hydrogen, or hydrogen sulfide gas to be overpopulated in the small intestine and produce the symptoms of SIBO. Conventional SIBO Treatment: The conventional approach to SIBO treatment includes oral antibiotics with or without a low-FODMAP diet. A low-FODMAP diet involves eliminating foods high in certain fermentable sugars that feed many types of bacteria. Many individuals with SIBO experience adverse symptoms, such as abdominal bloating, pain, brain fog, etc. after eating foods high in FODMAPs. Eliminating or minimizing foods containing FODMAPs can help reduce the severity of symptoms while treating SIBO. Antibiotics that may be used to treat SIBO include, rifaximin, neomycin, metronidazole, and others. The use of antimicrobial herbs to treat SIBO has become more popular due to the ineffectiveness of oral antibiotics to completely eradicate SIBO. SIBO Testing & Treatment at Restorative Medicine: Dr. Miranda Hill utilizes a form of applied kinesiology known as Cellular Photonics to test and formulate treatment plans for SIBO. Dr. Miranda Hill utilizes various forms of therapies to treat SIBO, including herbs, supplements, enzymes, binders, homeopathics, PEMF therapy, and/or medications. Dietary modifications are individualized based on each patient’s case. Following a low-FODMAP diet is not required in every case of SIBO. Dr. Miranda Hill specializes in supporting the immune system and other areas of the body while treating SIBO. Treatment plans are comprehensive and inclusive to the whole person. Contact our office for more information about scheduling an appointment with Dr. Miranda Hill. References: Simrén M, Stotzer PO. Use and abuse of hydrogen breath tests. Gut. 2006;55(3):297-303. doi:10.1136/gut.2005.075127 Lim J, Rezaie A. Pros and Cons of Breath Testing for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth. Gastroenterol Hepatol (N Y). 2023;19(3):140-146.

What is Homeopathy? Homeopathy is a form of medicine that uses very dilute substances at low and ultra low doses to stimulate healing within the body. Homeopathic medicine has been used for hundreds of years. National health systems of Brazil, Chile, Cuba, India, Mexico, Nigeria, Pakistan, South Africa, and Switzerland regularly use homeopathy as part of healthcare. Traditional homeopathic remedies contain nanoparticles (very small particles) of the original substance from which the medicine is derived from. In the body, homeopathic nanoparticles can treat acute and chronic infections, support optimal organ and immune function, correct dysfunctional cellular patterns, and promote drainage. Homeopathy can also be prepared through electromagnetic imprinting of alcohol or water. This form of homeopathy works by shifting the positive and negative charges lining cells throughout the body, supports detoxification, increases drainage, improves immune function, and can directly treat acute and chronic infections. Homeopathics may be prepared from plants, minerals, vitamins, microorganisms, animal derivatives, root canals post extraction, hormones, peptides, etc. Dr. Miranda utilizes homeopathy with patients to address underlying causes and to treat many conditions. Homeopathy is a very gentle form of medicine that is dosed based on the condition and the state of the body. Dr. Miranda Hill personalizes each homeopathic blend and sources homeopathics from around the world. Homeopathy May Be Used For The Following Indications: Detoxification Optimizing digestion - treating constipation, diarrhea, abdominal pain, bloating, etc. Regulating organ function Drainage of body systems - lymphatics/spleen, liver, gastrointestinal tract, cardiovascular system, etc. Treatment of acute or chronic infections - bacteria, viruses, and parasites Balancing of the immune system Regulating hormones Alleviating acute or chronic pain Treatment of many dental conditions Aid healing of tissues - post surgery, wounds, cuts, lacerations, trauma, bites, etc. Supporting emotional health Improving sleep Traditional Homeopathic Dosages: Dr. Miranda Hill utilizes a variety of homeopathic dosages as a part of a comprehensive treatment plan. Homeopathics vary in dilution and strength. The following is a key to the numeric homeopathic dosage system: A homeopathic remedy with a number followed by “X” or “D” is diluted based on a 1:10 ratio A homeopathic remedy with a number followed by “C” or “cK” is diluted based on a 1:100 ratio A homeopathic remedy with a number followed by “M” is diluted based on a 1:1,000 ratio A homeopathic remedy with a number followed by “LM” is diluted based on a 1:50,000 ratio The first number in the ratio refers to the original substance, while the second number refers to the alcohol or water base used to prepare the homeopathic remedy. Homeopathics are made by preparing a mother tincture out of the raw material (e.g. plant material) and then taking one drop of the mother tincture and combining it with alcohol or water - nine drops for a X remedy, 99 drops for a C remedy, 999 drops for a M remedy, or 49,999 drops for a LM remedy. This would produce a 1X, 1C, 1M, or 1LM homeopathic depending on the relative amount of alcohol or water used. The dilution process continues until the number of dilutions coincides with the respective number on the homeopathic. For example, five more dilutions would occur from a 1X preparation to produce a 6X remedy. Some homeopaths believe that beyond a potency of 12C, such as 30C, 200C, 1M, or higher dilutions, molecules of the original substance are no longer present in the homeopathic. Studies have shown nanoparticles of the original substance to persist in homeopathic medicines of high dilution. A commonly held belief in homeopathy is that highly dilute homeopathics, such as 1M, are stronger than less dilute homeopathics, such as 6X. The strength of a homeopathic remedy does not always depend on the number of dilutions. Homeopathic potency depends on multiple variables within the body, the quality of the remedy, and how the remedy is prepared. Factors That Alter How Homeopathics Work In The Body: Genetics The state of liver detoxification and total body burden The state of the immune system at the time of taking a homeopathic Allergies Hormonal fluctuations Cellular membrane integrity The amount of inflammation in the body (acute vs. chronic inflammation) Specific toxins in the body, such as environmental chemicals, heavy metals, mycotoxins, biotoxins, etc. Chronic infections Quality of the homeopathic remedy Alcohol vs water base of the homeopathic (alcohol preserves homeopathics better than water) The source and quality of the original substance used to prepare the homeopathic Form of homeopathic used - liquid vs. pellets / dissolvable tablets Individualized Homeopathy At Restorative Medicine: Dr. Miranda Hill utilizes many homeopathics as part of a comprehensive treatment plan with patients. Dr. Miranda Hill sources homeopathics from around the world. Homeopathics help condense the number of therapies in a treatment plan since they are diverse and broad in action. Homeopathic medicine can expedite treatment and reduce the severity of symptoms. Inquire about homeopathic medicine by contacting Restorative Medicine’s office. References: Vassighi N. Homeopathy Basics. 2020. Chikramane PS, Suresh AK, Bellare JR, Kane SG. Extreme homeopathic dilutions retain starting materials: A nanoparticulate perspective. Homeopathy. 2010;99(4):231-242. doi:10.1016/j.homp.2010.05.006 

The incidence of food intolerances has grown at an exponential rate over the last decade. Common food intolerances include dairy, gluten/wheat, eggs, soy, corn, tree nuts, peanuts, sugar, etc. Food intolerances are different from anaphylactic allergies, which are life threatening. Having a food intolerance produces non-life threatening symptoms, which may be immediate or delayed upon ingestion or contact with the specific food. Causes of Food Intolerances: The development of food intolerances may occur within days of an acute exposure or can be gradual over time. The acute development of food intolerances may be preceded by ingestion of bacterial toxins, known as endotoxins or exotoxins, or harmful microorganisms, such as aggressive strains of bacteria, viruses, or parasites. Many people who experience food poisoning go on to develop multiple food sensitivities. Food intolerances that develop over time may involve microbial imbalances in the gastrointestinal tract, increased gastrointestinal lining permeability, impaired liver detoxification, altered immune function, and/or toxins in the body. Environmental toxins, including pesticides, herbicides, and industrial grade chemicals, are some of the main drivers of food intolerances. Environmental toxins contribute to food intolerances by impacting the liver’s ability to detoxify, suppressing the immune system, killing beneficial microflora, and separating the tight junctions within the lining of the gastrointestinal tract (commonly referred to as leaky gut). Food intolerances occur when the body reacts to certain proteins in food. Some proteins are more reactive than others based on particle size, density, and similarity to self proteins in the body. When the tight junctions in the gastrointestinal tract lining separate, large proteins from food infiltrate into the blood supply and lymphatics underneath the gastrointestinal tract. Immune cells see the large proteins that leaked through the gastrointestinal tract lining as foreign and heighten an immune response. As a result, the body becomes overreactive to certain foods. Fats and sugars can also lead to food intolerances by feeding harmful strains of bacteria in the gastrointestinal tract that produce endotoxins or exotoxins. Common Symptoms of Food Intolerances: Abdominal bloating Abdominal pain Constipation Diarrhea Gas Nausea Fatigue Headaches or migraines Brain fog Anxiety ADD / ADHD Hyperactivity Mood swings Behavioral issues in children Heart palpitations Elevated heart rate Chronic pain Skin rashes Eczema Dry skin Itching Hair loss Increased mucus production or sinus drainage Sinus congestion Post nasal drip Swelling Chronically enlarged lymph nodes Poor immune function Weight gain or inability to lose weight Food Intolerance Treatment: Treating food intolerances involves addressing the underlying imbalances in the body, such as removing harmful microorganisms (bacteria, viruses, and/or parasites), balancing immune function, and supporting elimination pathways. Most people are able to add the foods they were sensitive to back into their diet within six months of treatment. Treatment modalities for food intolerances may include cell therapies (organ specific peptides), supplementation, medications, homeopathy, herbal medicine, and/or nutritional therapy. Having a diverse diet is possible through individualized treatment. Schedule an appointment with Dr. Miranda Hill here to get started.

Over the last decade gluten has become one of the most common food intolerances world wide. Gluten is a protein, found in many grains, including wheat, barley, rye, etc. Many individuals develop gluten sensitivity over time. Gluten sensitivity is different from a true allergy, and usually involves delayed symptoms after exposure. The process by which gluten sensitivity occurs is related to the state of the immune system, the total toxic load in the body, chronic infections, and gut permeability. Gluten is a protein composed of prolamin and glutelin. These proteins are dense and sticky. Hundreds of years ago, wheat contained five times less gluten than it does today. The combination of increased gluten content and the use of pesticides on our food has set the stage for shifts in the immune system and hyperreactivity. Many modern day strains of wheat have been chemically hybridized. This is different from genetically modified organisms, as there is no foreign DNA inserted into the plant genome. Clearfield Wheat is a strain of wheat that has been genetically altered using the toxic chemical sodium azide. Sodium azide is an extremely volatile substance that is explosive and is known to cause cancer. Clearfield Wheat is commonly grown throughout the United States. Due to many factors in the environment, including the use of herbicides, pesticides, and fungicides, immune tolerance within the body shifts. The body becomes reactive to certain proteins, such as gluten, when toxins interfere with cell signaling and the normal function of the immune system. When the immune system shifts into a reactive state, food sensitivities develop. Ancient strains of wheat, such as einkorn, naturally contain less gluten. Einkorn wheat is not commonly used in the United States because high amounts of gluten are favored in food manufacturing. Many strains of wheat have been cross bred to increase the gluten content of the grain. Cross breeding crops is different from chemical hybridization and does not involve the use of toxic chemicals. Modern strains of wheat that have not been chemically hybridized produce less inflammation in the body compared to those that have been chemically hybridized. This is one of the reasons people can travel to Europe and eat gluten without developing adverse symptoms. In the United States, certified organic products are not allowed to contain ingredients that have been chemically hybridized and is the best way to avoid Clearfield Wheat. Treating food sensitivities involves balancing the immune system while treating underlying root causes. The symptoms of gluten intolerance vary depending on the total toxic load in the body and the status of the immune system. Common symptoms of gluten intolerance include adverse symptoms after eating gluten, abdominal pain, bloating, gas, weight gain, diarrhea, constipation, headaches, and/or skin conditions. Depending on the severity of the gluten intolerance, additional symptoms may continue to present over time. Most people can add gluten back into their diet when the underlying root causes and imbalances are addressed. Dr. Miranda Hill works with patients to identify food sensitivities and the underlying causes. With individualized treatment, food sensitivities resolve and patients are able to enjoy a diverse diet without symptoms. Schedule an appointment with Dr. Miranda Hill here .

Heavy metals are a common underlying cause of many chronic health conditions. Heavy metals can build up in the body over long periods of time or may remain in the body after acute exposures. This article includes common symptoms and conditions caused by heavy metal toxicity. Symptoms of heavy metal toxicity are highly dependent upon the individual and other underlying factors, including chronic infections and environmental toxins. This article does not include symptoms of acute heavy metal poisoning. Aluminum When heavy metals build up in the body, chronic inflammation protects tissues from the damaging effects of the metal particles. Aluminum, like all heavy metals, may remain deep within the body for decades. Aluminum disrupts enzymatic cellular reactions and impairs overall detoxification. Aluminum is a neurotoxin and can contribute to chronic widespread pain and neuropathy. Over time, aluminum can alter chemical signaling between cells, promoting an autoimmune response. Many autoimmune diseases have underlying heavy metals as part of the root cause. Heavy metals alter the way the immune system behaves and shifts the immune system into a reactive state. The symptoms of aluminum toxicity include: Anxiety Depression Fatigue Brain fog Poor concentration Memory loss Chronic pain Chronic allergies Food sensitivities Multiple chemical sensitivity Lowered immune function Skin rashes Eczema High histamine Aluminum toxicity is commonly associated with the following medical conditions: Alzheimer’s disease Parkinson’s disease Amyotrophic lateral sclerosis (ALS) Memory loss Asthma Cardiovascular disease High cholesterol High blood pressure Multiple sclerosis Kidney disease Osteoporosis Arsenic Arsenic is commonly found in contaminated water supplies, some spices, specific geographic regions with high soil content, and some foods. Arsenic depletes cellular energy (mitochondrial function), promotes chronic inflammation, impairs pancreatic function, and increases nervous system inflammation. Many forms of chronic fatigue syndrome involve arsenic as a part of the driving cause. Arsenic is also involved in many cardiovascular conditions, as arsenic promotes vascular inflammation and stress. Arsenic inhibits the transfer of beneficial cholesterol and promotes high levels of circulating oxidized lipid particles within the body. Arsenic exposure is common and can be easily mitigated through water filtration and addressing other imbalances in the body. Arsenic is a known carcinogen. Heavy metal detoxification is essential for all cancer patients to address the underlying immune stressors. Cadmium Cadmium is a heavy metal that can be involved in many cardiovascular conditions, asthma, cancer, diabetes, kidney disease, liver disease, lowered immune function, autoimmune diseases, and learning disorders. Symptoms of cadmium toxicity may include: Brain fog Fatigue Anxiety Depression Low libido Decreased muscle strength Joint pain Nerve pain Abdominal pain Decreased coordination Neuropathy Anemia Cadmium disrupts multiple reactions inside of cells and promotes chronic inflammation. Overtime, cadmium alters the immune system’s ability to survey for cancer cells. Cadmium is extremely toxic to the nervous system and may promote neurodegenerative conditions. Cadmium may also be involved in many gastrointestinal disorders by interfering with the production of digestive enzymes requiring zinc. Many individuals with heavy metals sitting within the gastrointestinal tact lining experience abdominal pain, bloating, gas, and/or burping. Heavy metals interfere with the immune system located in the gastrointestinal tract, thereby promoting the growth of fungal species and unfriendly bacteria. Cobalt Cobalt is a heavy metal that can be found in various forms. A very small amount of cobalt is essential to normal functions within the body. Excessive amounts of cobalt can build up in the body and cause a variety of adverse health effects. High amounts of cobalt in the body have been associated with the following conditions: Cancer Gastrointestinal conditions (including Crohn’s disease and Colitis) Cardiovascular disease Cardiomyopathy Chronic pain Joint pain Muscle pain Nerve pain Postural orthostatic tachycardia syndrome (POTs) Raynaud’s syndrome Asthma Lowered immune function or chronic infections Neuropathy Kidney disease Liver disease Altered function of the pancreas (including diabetes) COPD Anemia Cobalt interferes with many chemical reactions in the body and alters cellular communication. Typically, one of the most prominent symptoms of cobalt toxicity is widespread pain. Many individuals with cobalt toxicity are diagnosed with the blanket diagnosis of fibromyalgia, for which the cause is unknown. Cobalt toxicity irritates the nervous system and can cause nerve damage. Cobalt interferes with cellular oxygenation and can result in chronic anemia of unknown origin. Due to cobalt’s effects on the nervous system and cardiovascular system, many individuals may experience the following symptoms: Dizziness Nausea Vomiting Tremors Anxiety Depression Brain fog Poor circulation Numbness Tingling Shortness of breath Decreased range of motion Decreased hearing Impaired vision Cobalt is also destructive to the cardiovascular system and promotes systemic inflammation. Detoxifying cobalt out of the body is essential to the management of any condition with cobalt related toxicity. Copper Copper is an essential mineral that is needed to maintain the production of red blood cells, immune cells, collagen, and nerve cells. In excess, copper can build up in the body and lead to a host of chronic conditions. Symptoms of copper toxicity may include: Fatigue Anxiety Depression Mood swings Hyperactivity Brain fog Memory loss Dizziness Pale or yellowing skin Joint pain Nerve pain Neuropathy Chest palpations Chest pain Low blood pressure Feeling cold all the time Nausea Diarrhea Abdominal pain Hair loss Dry skin Skin rashes Changes in eye color High levels of copper may be involved in the following conditions: Alzheimer’s disease Parkinson’s disease Autoimmune diseases Cardiovascular disease Small vessel disease High blood pressure Arrhythmias Anemia Rheumatoid arthritis Osteoarthritis Asthma Autism Learning disabilities Miscarriages Liver disease Kidney damage Cancer Excess copper disrupts the body’s copper to zinc ratio. Too much copper can decrease zinc absorption and lead to a zinc deficiency. The opposite is also true. Too much zinc can cause a copper deficiency. Supplementing with high amounts of copper or zinc for more than three weeks on average can disrupt the ratio between copper and zinc. The build up of copper in the body can be associated with a genetic condition called Wilson’s disease. Wilson’s disease is a rare inherited condition resulting in poor copper elimination from the body. Identification of Wilson’s disease is performed through blood and urine testing. Iron Iron is an essential mineral that is involved in the production of red blood cells. Too much iron can build up in the body through genetic conditions, such as hemochromatosis, chronic infections, high levels of chronic inflammation, heavy metal toxicity, excess supplementation, and cancer. Having enough iron stored in the body is essential for everyday life; however, too much iron leads to oxidation and damage of tissues. The combination of excess iron and chronic persistent infections produces high amounts of inflammation. The combination of excess iron and chronic infections, such as Lyme disease, bartonella, ehrlichia, rickettsia, mycoplasma, EBV, some parasites, and others, can lengthen treatment duration. Iron can serve as a nutrient source for chronic infections, increasing their activity. Chronic infections can also limit the body’s ability to detoxify excess iron. Treating chronic infections is a key factor in managing iron levels in the body. Symptoms of chronic iron excess include: Fatigue Chronic pain Brain fog Memory loss Headaches Migraines Anxiety Depression Learning disabilities Insomnia Tremors Dizziness Constipation Abdominal pain Cold intolerance Hair loss Yellowing of skin (jaundice) Conditions associated with chronic iron excess: Alzheimer’s disease Parkinson’s disease Amyotrophic lateral sclerosis (ALS) Multiple sclerosis ADD / ADHD Cardiovascular disease Cardiomyopathy Small vessel disease High cholesterol High blood pressure High blood inflammatory markers Hemochromatosis Hepatitis Liver cirrhosis / liver disease Pancreatitis Cancer Lead Lead is a heavy metal that is very destructive to the body. Lead is a neurotoxin and has been associated with the following symptoms: Fatigue Hyperactivity in children Anxiety Depression Low IQ Aggression Irritability Brain fog Poor concentration Memory loss ADHD / ADD Headaches Migraines Chronic pain (joint pain, bone pain, muscle pain, or nerve pain) Pain of organ origin (kidney pain, liver pain, gallbladder pain, pancreatic pain, etc.) Tachycardia Tremors / ticks Seizures Numbness Tingling Neuropathy Muscle weakness Decreased balance Poor coordination Swelling Abdominal pain Nausea Vomiting Hair loss Decreased hearing Decreased urination Eczema Easy bruising Low libido Decreased appetite Lowered immune function Lead may be a major factor involved in fibromyalgia and other chronic pain syndromes. Lead disrupts cell signaling and increases the production of pro-inflammatory pain signals. Treating lead toxicity can greatly improve pain and the quality of life in such conditions. Lead may be involved in the following medical diagnoses: Cardiovascular disease Vascular stenosis Raynaud’s syndrome High blood pressure High cholesterol Autism Developmental delays (cognitive and stature) Gout Hypothyroidism Kidney disease Liver disease Autoimmune diseases Arthritis Amyotrophic lateral sclerosis (ALS) Multiple sclerosis Mental health conditions (bipolar, schizophrenia, personality disorder, etc.) Osteoporosis Cancer Lead is highly associated with learning disabilities and behavioral challenges in children. Lead toxicity can be a large factor in autism progression. If not treated, lead can also suppress a child’s growth. For children with lead toxicity, addressing lead and other heavy metals can improve behavior, mood, cognition, energy, academics, and ability to socialize. Mercury Mercury is an extremely toxic heavy metal that is commonly used in dentistry, found in many large fish, and may be an airborne contaminant. Symptoms of mercury toxicity include: Anxiety Depression Mood swings Fatigue Brain fog Poor concentration Memory loss Headaches Migraines Insomnia Tremors Seizures Chronic pain Muscle weakness Heart arrhythmias Tachycardia Blood sugar dysregulation Nausea Metallic taste in mouth Increased thirst Swelling Dry mouth Excessive salivation Excessive sweating Heat intolerance Foul body odor Acne Hair loss Hearing loss Light and sound sensitivity Easy bruising Low libido Lowered immune function Mercury toxicity may be involved in the following health conditions: Autoimmune diseases Arthritis Amyotrophic lateral sclerosis (ALS) Multiple sclerosis Mental health conditions (bipolar, schizophrenia, personality disorder, etc.) ADD / ADHD Developmental delays Cardiovascular disease Vascular stenosis High blood pressure Postural orthostatic tachycardia syndrome (POTs) Kidney disease Osteoporosis Detoxing mercury has to be done with the utmost care. Mercury damages tissues upon being mobilized if not done correctly. Heavy metal chelators, such as EDTA, DMPS, and DMSA, pull heavy metals from tissues within the body. These chelators are commonly used for individuals with high amounts of mercury or lead in the body. Strong chelators deplete the body of essential trace minerals and come with the risk of mobilizing mercury and other heavy metals into other areas of the body. There are far too many risks that come with utilizing strong chelators, such as EDTA, DMPS, and DMSA, orally or intravenously. Nickel Nickel is a heavy metal that is commonly associated with chronic inflammatory conditions and immune hypersensitivity. Nickel is irritating to soft tissues and can lead to chronic swelling. Nickel contributes to high amounts of oxidative stress in the body and interferes with many enzymatic reactions essential for cell signaling. Nickel toxicity may present with the following symptoms: Anxiety Panic attacks Fatigue Chronic pain Dizziness Tremors Headaches Eczema Skin rashes Chronic allergies Lowered immune function The following health conditions may involve nickel toxicity: Autoimmune diseases Cardiovascular disease Small vessel disease High cholesterol High blood pressure Multiple sclerosis Kidney disease Cancer Tin Tin is a heavy metal associated with multiple conditions relating to the cardiovascular system. Tin interferes with enzymatic reactions and disrupts the function of mitochondria. Tin is a neurotoxin and can contribute to many of the following symptoms: Fatigue Anxiety Depression Brain fog Poor concentration Memory loss Headaches Migraines Developmental delay Chronic pain Low blood sugar Tremors Seizures Dizziness Numbness Tingling Skin rashes Tin may be an underlying component of the following health conditions: Autoimmune diseases Autism Arthritis Amyotrophic lateral sclerosis (ALS) Cardiovascular disease Raynaud’s syndrome High cholesterol High blood pressure Kidney disease Liver cirrhosis Cancer Titanium Titanium is a heavy metal involved in many chronic inflammatory conditions. Titanium increases cellular stress and whole body inflammation. Titanium is commonly used as a whitening agent in food products, medications, supplements, beauty products, and personal care items. Symptoms of titanium toxicity include: Anxiety Irritability Mood swings Nervousness Chronic pain Fatigue Headaches Migraines Tremors Dizziness Neuropathy Decreased balance Poor coordination Nausea Swelling Skin rashes Low libido Lowered immune function Medical conditions that may be caused by titanium toxicity: Autoimmune diseases Arthritis Autism Amyotrophic lateral sclerosis (ALS) Cardiovascular disease High cholesterol High blood pressure Pancreatitis Cancer Heavy Metal Detoxification: Most heavy metal treatments take two to four years and may utilize very harsh chelating agents. Dr. Miranda Hill has extensively studied the best therapies to treat heavy metal toxicity in the safest way possible. Heavy metal detoxification utilizing Dr. Miranda’s individualized treatment plans averages six to eight months. Treatment includes targeted and specific mobilizers, binders, anti-inflammatory agents, cellular stabilizers, and nutrient repletion throughout the metal removal process. Dr. Miranda Hill does not utilize oral or intravenous EDTA, DMPS, or DMSA due to the extensive side effects and associated cellular damage. Schedule an appointment with Dr. Miranda Hill here for heavy metal toxicity assessment and treatment. Learn more about environmental sources of heavy metals here .

Starting the new year often correlates with kick-starting health goals and initiating weight loss. Many people set out to improve their health, but navigating the expansive network of health information can become overwhelming. Many people feel stuck after trying and investing in countless diet trends without lasting impact. The missing piece to most weight management programs is individualization. Every person is unique. What may work for one person may not necessarily be the ideal solution for another. This is where naturopathic doctor Miranda Hill can tailor specific interventions for individuals based on their specific needs. For many people calorie counting and exercise no longer budge the scale. What once worked to drop extra pounds may no longer be effective. Long-term dieting and environmental toxins alter hormone signaling and the microbiome within the gastrointestinal tract. The delicate balance between hormones and the microbiome affects detoxification and the body’s ability to lose weight. Addressing gut health and environmental toxins are the first steps to lasting weight loss. Today’s world does not look anything like the world of fifty years ago. The amount of environmental toxins given off around the globe has grown exponentially decade after decade. Daily exposure to environmental toxins has set the stage for weight gain and chronic health conditions. Environmental toxins, including pesticides, petroleum by-products, heavy metals, mycotoxins, and many other chemicals disrupt the microbiome and the body’s ability to detoxify. Optimal detoxification is one of the most important factors for natural weight loss. Weight loss has become more of an issue of detoxification, rather than an issue of calorie restriction. This is why so many people struggle to lose weight despite making healthy food choices and counting calories. Another factor that plays a large role in overall health and weight management is chronic infections. Many infections have the capability of becoming chronic in nature. Infections, such as those from insect bites, select upper respiratory infections, and some gastrointestinal infections, can remain dormant in the body for years. These infections may include viruses, bacteria, and parasites. Overtime, chronic infections promote a constant state of inflammation in the body. Consistent states of inflammation in the body changes the metabolism of hormones and how toxins are processed; in turn, it is more challenging to lose weight. Treating underlying chronic infections is an important part of a successful weight loss plan. This year, begin your health and wellness goals with individualized care from naturopathic doctor Miranda Hill at Restorative Medicine. Dr. Miranda Hill specializes in identifying root causes to many health conditions. To learn more about weight loss strategies and to start your weight loss journey, please contact Restorative Medicine's office. Original article posted in the January 2024 edition of the Liberty Lake Neighbors Magazine

Glyphosate, the active ingredient in Roundup, is one of the most common herbicides in the United States. Glyphosate is sprayed on crops, lawns, gardens, parks, school yards, roadsides, forests, and other landscapes. Since 1974, more than 19 billion pounds of glyphosate have been applied across the globe. Glyphosate can be found in rainwater, tap water, outdoor air, food, soil, textiles, personal care products, beauty products, contaminated supplements, umbilical cords of newborns, and many other sources. Glyphosate is widely used in conventional farming, including genetically modified organisms (GMOs), some non-GMO crops, and textile plants. Farmers may spray glyphosate on non- GMO crops prior to harvest to dry the plant material, making harvesting easier. Non-GMO foods commonly sprayed with glyphosate prior to harvest include, wheat, oats, barley, rye, flax, legumes, canola, sunflower, safflower, and linseed. Glyphosate Depletes Essential Minerals and Promotes Heavy Metal Toxicity Glyphosate impairs the ability for plants to uptake minerals from the soil and decreases plant nutrient density. Additionally, glyphosate acts as a chelator, which means glyphosate binds and removes minerals from the soil and the body, even in small quantities. These factors have contributed to the widespread deficiency in many minerals in the body and soil, including magnesium, zinc, copper, cobalt, manganese, and iron. Since glyphosate is a chelator, it also has the ability to bind heavy metals and transfer them into the body. Glyphosate binds to aluminum one million times more than the metal chelator EDTA. Glyphosate wraps around heavy metals and escorts the molecules across the gastrointestinal tract, where the heavy metals are released into various tissues. Glyphosate Fungal Connection Glyphosate disrupts the delicate balance of microorganisms in the soil. Researchers are beginning to see an overall shift in the bacterial and fungal species naturally present in soil. Glyphosate kills beneficial bacteria and favors the growth of aggressive fungal species that produce toxic mycotoxins. Fusarium and Aspergillus are just two types of fungi that have been associated with glyphosate use. Fusarium fungi produces the mycotoxin called zearalenone that is a potent endocrine disrupter, linked to multiple cancers, and is immunosuppressive. Read more about the health effects of mycotoxins here . Health Impacts of Glyphosate Glyphosate is very difficult for the body to process and eliminate. Upon exposure, glyphosate displaces the amino acid glycine in many tissues and impairs respective function. Glyphosate has been labeled as a probable carcinogen by the World Health Organization. Glyphosate directly damages DNA, which can lead to cellular mutations and ultimately cancer. Over time, glyphosate can dysregulate the part of the immune system involved in cancer cell surveillance. Multiple studies have shown glyphosate to be involved in breast cancer, forms of lymphoma, leukemia, liver cancer, melanoma, thyroid cancer, pancreatic cancer, kidney cancer, bladder cancer, and colon cancer. Prior to being utilized as a herbicide, glyphosate was patented as an antibiotic. Glyphosate has been shown to disrupt the microbiome, contribute to leaky gut, impair liver detoxification (suppresses cytochrome P450), deplete sulfur levels, and contribute to many adverse health conditions. Glyphosate has been shown to be involved in the following health conditions: Depression Anxiety Lowered immunity Autoimmune diseases Autism Cancer Food sensitivities Allergies Multiple chemical sensitivities Hair loss Skin rashes Chronic pain Chronic fatigue Brain fog Constipation Diarrhea Abdominal pain Conditions of the gallbladder Small intestinal bacterial overgrowth (SIBO) Persistent fungal infections Celiac disease Hypothyroidism Hormone imbalances Birth defects Miscarriages Cataracts Chronic kidney disease Kidney failure Mineral deficiencies Heavy metal toxicity Osteopenia Osteoporosis Cardiovascular disease Liver disease Obesity Diabetes Multiple sclerosis Alzheimer’s disease Parkinson’s disease Glyphosate’s Link to Gluten Intolerance, Celiac Disease, & Autoimmunity The steady rise in gluten intolerance has been commonly linked to the increased gluten content of modern day wheat products. Many health conscious advocates promote ancient grains as an alternative to the widespread forms of hybridized wheat or a gluten free diet. The missing piece is asking why so many people are commonly reacting to gluten and other foods. Is gluten really the culprit or is there another underlying root cause? The gluten content of some strains of wheat has increased, but so has the amount of herbicides, pesticides, and fungicides that have been applied to grains in general. Glyphosate is very irritating to the body and causes a chronic allergic response. Over time, glyphosate damages the intestinal wall by killing beneficial flora and damages the intestinal lining. One of the main underlying causes to gluten intolerance and many other food sensitivities are the herbicides (including glyphosate), pesticides, and fungicides sprayed on food. Dr. Miranda Hill helps patients address the underlying causes, including glyphosate buildup in the body, to add gluten back into the diet. Celiac disease has been on the rise since the mid 1990s, right in line with the increased use of glyphosate. The etiology of celiac disease involves microbiome imbalances (i.e. dysbiosis), leaky gut (i.e. damage to the intestinal wall), poor nutrient absorption, chronic infections, immune shifts, chronic allergic response, and the build up of environmental toxins (including glyphosate). Glyphosate detoxification is a key piece of the comprehensive treatment plan for celiac disease. The role of glyphosate in autoimmune conditions, especially irritable bowel disease, is commonly missed. Glyphosate suppresses the innate immune system, favors the growth of pathogenic species in the gastrointestinal tract, and increases systemic inflammation. Overtime, the combination of chronic exposure to glyphosate and other inciting factors can shift the immune system to produce autoantibodies and attack host tissue. Detoxing glyphosate, among other pesticides, herbicides, and fungicides, is essential to normalizing immune function in all autoimmune conditions. Glyphosate and Product Labels Many natural based food products are certified by The Non-GMO Project and display a butterfly logo on the packaging. The Non-GMO Project label does not mean the product is free from glyphosate. Items certified by The Non-GMO Project cannot contain GMOs, but can be sprayed with pesticides, herbicides, or fungicides. Certified organic crops restrict the use of glyphosate. Choosing organic products limits glyphosate exposure; however, organic products can be contaminated with glyphosate due to airborne spread when growing in close proximity to conventionally sprayed crops. Many processed food products now have the following fine print statement on the packaging, “ingredients derived from a bioengineered source.” These food products contain GMOs and are likely contaminated with glyphosate and other pesticides, herbicides, and/or fungicides. For glyphosate-free certified products, see The Detox Project for more information. Residential Use of Roundup Using Roundup and other pesticides around the home is a huge exposure that contributes to the total toxic load in the body. Upon spraying Roundup, particles become airborne and may be inhaled or come in contact with the skin. Spraying Roundup on driveways, lawns, and gardens can track glyphosate into the home and expose family members and pets. As glyphosate seeps into the soil, ground water becomes contaminated. Glyphosate is extremely toxic to wildlife and can cause kidney failure in small animals. For weed control, use vinegar as a natural alternative to Roundup. Glyphosate Detoxification As a comprehensive part of treatment plans, Dr. Miranda Hill works with patients to detox glyphosate out of the body. There are many therapies and natural agents that can be utilized to promote the elimination and breakdown of glyphosate. Schedule an appointment with Dr. Miranda Hill here for glyphosate detoxification and comprehensive treatment. References: Seneff S. Toxic Legacy: How the Weedkiller Glyphosate Is Destroying Our Health and the Environment. Chelsea Green Pub Co; 2023. Samsel, Anthony & Seneff, Stephanie. (2016). Glyphosate pathways to modern diseases V: Amino acid analogue of glycine in diverse proteins. Journal of Biological Physics and Chemistry. Volume 16. 9-46. 10.4024/03SA16A.jbpc.16.01. Samsel, Anthony & Seneff, Stephanie. (2015). Glyphosate, pathways to modern diseases IV: cancer and related pathologies. Journal of Biological Physics and Chemistry. 15. 121-159. 10.4024/11SA15R.jbpc.15.03. Samsel, Anthony & Seneff, Stephanie. (2013). Glyphosate's Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases. Entropy. 15. 1416-1463. 10.3390/e15041416. Gunatilake S, Seneff S, Orlando L. Glyphosate's Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin. Int J Environ Res Public Health. 2019;16(15):2734. Published 2019 Jul 31. doi:10.3390/ijerph16152734 Samsel A, Seneff S. Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intolerance. Interdiscip Toxicol. 2013;6(4):159-184. doi:10.2478/intox-2013-0026

Many forms of cookware, including pots, pans, bakeware, and electric cooking appliances, contain toxic chemicals and heavy metals. With continual use and heat application, certain forms of cookware release toxins into food, beverages, and the air. These toxins and heavy metals have many negative health impacts. Navigating non-toxic cookware marketing claims can be challenging. The following information outlines which forms of cookware to avoid, as well as recommended cookware materials and brands. Cookware to Avoid: Teflon or Non-Stick : Teflon and most non-stick cookware contain perfluorinated compounds (PFAS), including perfluorooctanoic acid (PFOA) and polytetrafluoroethylene (PTFE). Upon being heated, non-stick cookware releases PFAS into the food and air, which are absorbed into the body. Perfluorinated compounds are considered “forever chemicals,” which means that they persist in the environment and are difficult for the body to process. Perfluorinated compounds may be involved in many health conditions, including acne, ADD, ADHD, altered immune function, autoimmune diseases, cardiovascular disease, high cholesterol, high triglycerides, estrogen dominance, PCOS, fatty liver disease, hypothyroidism, cancer, kidney damage, weight gain, etc. Many electric griddles, pancake makers, waffle makers, bread machines, rice cookers, toaster ovens, air friers, Instant Pots, and standing milk frothers are made with non-stick materials. Opt for brands made with stainless steel or those from the recommended brands listed below. Nano Titanium Ceramic Coatings : Certain ceramic coatings are made with titanium nanoparticles, which leach into food when heated. Titanium is a heavy metal linked to many health conditions, including acne, anxiety, depression, brain fog, chronic pain (including muscle and joint pain), osteoarthritis, migraines, poor liver detoxification, blood sugar dysregulation, chronic inflammation, tremors, autoimmune diseases, etc. Aluminum Pots, Pans, and Bakeware : Upon exposure to heat, aluminum transfers to food. High levels of aluminum in the body can lead to nervous system disorders, ADD, ADHD, chronic pain, chronic fatigue, brain fog, headaches, autoimmune conditions, immune system dysregulation, kidney disease, hypertension, high cholesterol, cardiovascular disease, dementia, hypothyroidism, osteoporosis, anemia, cancer, impaired organ function, etc. Note: Avoid cooking with aluminum foil, as this is another source of aluminum exposure. Copper Pots, Pans, and Mugs : Copper does not require heat to transfer to liquids or food. Chronic exposure to high levels of copper can disrupt the body’s copper to zinc ratio. Additionally, high levels of copper can result in nervous system disorders, diarrhea, abdominal pain, hair loss, insomnia, brain fog, headaches, chronic fatigue, anxiety, depression, ADD, ADHD, brittle hair/nails, chronic inflammation, chronic pain (including joint and muscle pain), dementia, kidney damage, liver toxicity, autoimmune diseases, etc. Note: Avoid drinking out of copper mugs, as this can lead to high levels of copper in the body. Antique Pyrex and Ceramic Cookware : Many painted vintage Pyrex and ceramic cookware contains lead and/or cadmium, which transfers to food. Silicone Cookware : Silicone consists of a blend of silicon and other chemicals. Upon heating, silicone has been shown to release endocrine disrupting compounds. GreenPan : Despite non-toxic marketing claims, GreenPan’s non-stick coating contains several toxic chemicals, including silane, aluminum oxide, tetraethyl orthosilicate, and potassium titanate. Caraway : Caraway’s non-stick coating breaks down with use. This means the non-stick coating ends up transferring to the cooked food. Caraway claims their products to be non-toxic and free from a handful of chemicals and metals, but does not test their products as the coating breaks down. Recommended Cookware: Pots and Pans : Lodge Cast Iron, Le Creuset Enameled Cast Iron, Staub, Cuisinart Stainless Steel Instant Pot : Purchase the stainless steel inner cooking pot option Rice Cooker : Purchase rice cookers with a stainless steel inner cooking pot Bread Machine : Sana Smart Bread Maker with stainless steel baking pan Toaster Oven : Black + Decker 8-Slice Extra Wide Convection Countertop Toaster Oven Bakeware : Pyrex, Le Creuset, Pampered Chef Stoneware Griddle : Staub Cast Iron Double Burner Griddle Pan Waffle Maker : Cast Iron Baking Sheets : Stainless Steel, Pampered Chef Stoneware Muffin Pan : Stainless Steel, Cast Iron, or Pampered Chef Stoneware Storage Containers : Glass containers, such as Pyrex  References: Perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), and Related Chemicals. American Cancer Society. Accessed December 16, 2023. https://www.cancer.org/cancer/risk-prevention/chemicals/teflon-and-perfluorooctanoic-acid-pfoa.html. Addo Ntim, S. , Norris, S. , Scott, K. , Thomas, T. and Noonan, G. (2017), Consumer Use Effects on Nanoparticle Release from Commercially Available Nanoceramic Cookware, Food Control, [online], https://doi.org/10.1016/j.foodcont.2017.12.003 (Accessed December 15, 2023)

The methylenetetrahydrofolate reductase (MTHFR) gene codes for the MTHFR enzyme. The MTHFR enzyme is essential to a process in the body known as methylation. Methylation breaks down the amino acid homocysteine, using methylfolate (vitamin B9), to produce methionine, then glutathione. Mutations of the MTHFR gene affects the body’s ability to methylate, thus slowing down certain reactions in the body. Every person has their own genetic code consisting of thousands of genes. Each gene has a unique function to code for specific proteins in the body. Genes contain the information to produce hormones, enzymes, and many other molecules. There are two copies of each gene, one paternal gene and one maternal gene. Epigenetics defines the way certain genes are expressed in the body and how they can be turned on and off. Genetic expression is influenced by environmental exposures (i.e. toxins), infections, lifestyle, and previous or current traumas. The MTHFR gene is just one of many genes with possible variants that can affect the function of the overall gene. Since all genes in the body work together, having a MTHFR gene mutation does not necessarily mean health issues will occur. The two main MTHFR gene mutations that have been studied include, C677T and A1298C. Like all genes in the body, both C677T and A1298C have two copies. A single mutation is known as heterozygous, while two gene mutations is known as homozygous. Having one or two genetic mutations at various points throughout the MTHFR gene can decrease the body’s ability to methylate, and thereby breaking down homocysteine. MTHFR gene mutations can contribute to a variety of medical conditions, including anxiety, depression, elevated homocysteine, cardiovascular disease, sensitivity to certain medications, and intolerance to certain forms of B vitamins. Many practitioners recommend supplementing with high doses of methylfolate (vitamin B9) for those with MTHFR gene mutations. Supplementing with high doses of methylfolate can be helpful or extremely aggravating for certain individuals. Aggravations to supplemental methylfolate occurs when methylfolate jams or speeds up reactions in the body; this can be dependent upon other gene mutations besides MTHFR. Many people do not tolerate methylated vitamins, including methylfolate and methylcobalamin (vitamin B12). This is why there is no one-size-fits-all multivitamin or B complex. Individuals who are sensitive to methylated vitamins tend to tolerate supplemental folate in the form of folinic acid and vitamin B12 in form of hydroxycobalamin and/or adenosylcobalamin. Schedule an appointment with Dr. Miranda Hill here to identify which vitamins are right for you. Supplemental folate comes in many forms, including folinic acid, methylfolate, calcium folinate, and methylfolate. Folic acid is the synthetic form of folic acid commonly added to fortified food to prevent neural tube defects. Individuals who have MTHFR gene mutations should not consume folic acid. For those with MTHFR gene mutations, folic acid may contribute to anxiety, depression, mood swings, irritability, ADD, ADHD, and brain fog. For those with MTHFR gene mutations, supplementing with methylfolate is highly dependent upon many factors in the body. Before supplementing, Dr. Miranda Hill recommends increasing daily intake of natural sources of folate, including dark leafy greens. Like many genes, the function of MTHFR can be impacted by environmental toxins. Addressing underlying toxicities can improve the function of MTHFR without methylfolate supplementation.