Rickettsia is a bacterial infection transmitted by ticks, mosquitoes, spiders, mites, lice, fleas, chiggers, other insects, blood transfusions, or congenital transmission. Rickettsia lives inside of cells, which makes it challenging to identify and treat. Inside of cells, rickettsia, like many Lyme co-infections, disrupts cellular signaling and immune function. Overtime, the disruption of cellular processes leads to impaired detoxification and chronic inflammation.
Symptoms of Acute Rickettsia Infection:
Acute rickettsial illnesses have been defined by three main diseases, including Rocky Mountain spotted fever, Rickettsia Parker rickettsiosis, and Rickettsia 364D Pacific Coast Fever. Since rickettsia can be transmitted from insects with other infections, there are varying degrees of infection. Not all rickettsial infections cause the three main rickettsial illnesses. Chronic rickettsial infections may persist and lead to symptoms associated with chronic illness (see the next section).
Typical symptoms of main three rickettsial diseases include, fever, chills, headache, muscle pain, joint pain, nausea, vomiting, loss of appetite, a characteristic maculopapular skin rash, swollen lymph nodes, and abnormalities found on complete blood count (CBC) blood testing. Without treatment, acute severe infections with Rocky Mountain spotted fever can be deadly.
Symptoms of Chronic Rickettsia Infection:
Rickettsia is notorious for causing chronic pain. Symptoms may wax and wane depending on rickettsia's life-cycle. Listed below are common symptoms of chronic rickettsia infection.
Testing for Chronic Rickettsia:
Laboratory blood tests for rickettsial infections are extremely limited. Only a select number of rickettsia strains can be tested for. The testing selectivity is based upon which strains have the research to support the diagnosis of acute rickettsial infections. This makes diagnosing chronic rickettsia challenging, as there are hundreds of identified rickettsial strains.
Another factor that makes diagnosing chronic rickettsia infections difficult is most blood tests look at the immune response (antibodies) to the infection. Depending on the stage, location, and activity of rickettsia, an immune response may or may not show up on blood work.
Specialized laboratory testing for select rickettsia species is available; however, these tests come with a significant out-of-pocket expense and the accuracy of the tests are not perfect. Dr. Miranda Hill utilizes Cellular Photonics to assess for rickettsial infections, among other chronic infections and underlying causes, during patient appointments.
Treating Chronic Rickettsia:
Conventional rickettsia treatment focuses on the use of tetracycline antibiotics. Some physicians will prescribe long-term antibiotics for the treatment of Lyme and co-infections, including rickettsia. Due to the many side effects of using antibiotics long-term, Dr. Miranda Hill uses alternative antimicrobials in combination with immune therapies to treat rickettsial infections. Schedule an appointment with Dr. Miranda Hill here for chronic infection treatment and management.